logo

EPT related to trasplantation, HLA typing, KIR, chimerism and surface antigens of neutrophils & platelets, anti HLA, anti HPA and GSTT1

  • Low resolution typing of loci HLA-A, HLA-B (and HLA-C as an option), HLA-DRB1(optional: HLA-DRB3, HLA-DRB4, HLA-DRB5,HLA-DQA1, HLA-DQB1)

  • High resolution typing of loci HLA-A, HLA-B (and HLA-C as an option), HLA-DRB1(optional: HLA-DRB3, HLA-DRB4, HLA-DRB5,HLA-DQA1, HLA-DQB1, HLA-DPA1, HLA-DPB1).

    High resolution typing is defined as the identification of HLA alleles that encode the same protein sequence within the antigen binding site

    D1.4.1

    HLA alleles must be identified at the level of resolution which defines the first and second fields according to WHO nomenclature by at least resolving all ambiguities:

    D1.4.1.1

    Resulting from polymorphisms located within exons 2 and 3 for HLA class I loci, and exon 2 for HLA class II loci

    D1.4.1.2

    That encompass a null allele, wherever the polymorphism is located, unless it can be demonstrated that an expressed antigen is present on the cells

  • 2DL1, 2DL2, 2DL3 , 2DL4 , 2DL5 , 2DS1 , 2DS2 , 2DS3 , 2DS4 , 2DS5 , 2DP1 , 3DL1 , 3DL2 , 3DL3 , 3DS1 , 3DP1